The Effects of Rod and Round-Like Nanohydroxyapatites on Allium cepa Root Meristem Cells

نویسندگان

چکیده

Biomaterials are engineering products that widely used in many medical fields such as orthopaedic applications, facial and maxillofacial surgery, artificial heart parts, metal parts implantable devices. These materials medicine because they compatible with the organism, not allergic, resistant to physical chemical factors. Hydroxyapatites bioactive calcium phosphate ceramics tissues. To increase their bioactivity, nano-sized hydroxyapatite has been produced. Although there advantages use of nanoparticles field, potentially toxic effects these on environment human health concern. It is also one topics be investigated whether different forms same nanoparticle will cause differences genotoxicity. In this study, potential genotoxic rod round hydroxyapatites (nHAs) were evaluated Allium cepa Single Cell Gel Electrophoresis (COMET) method. According results, form nHA A. meristem root tip cells caused statistically significant genotoxicity at 25 ppm concentration terms tail density moment. This study showed small-sized-nanohydroxyapatite-induced cell death cepa. shown properties affect toxicity mechanisms.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Genotoxicity of Industrial Paint Effluent on the Root Meristem of Allium Cepa

The genotoxic effects of the industrial effluent from a paint (100%, 50%, 25%, 10%, 5%, 1%, 0.50% and 0.25%) manufacturing company in Ikotun, Lagos was evaluated using the root meristem cells of Allium cepa. chromosomal aberration assays were used to determine the mitotic index and chromosome aberration rate. There was a significant difference (p<0.05) in the average root length of Allium cepa ...

متن کامل

Chromosomal aberrations induced by Glycidol in Allium cepa L root meristem cells

Glycidol is used as a stabilizer in the manufacture of vinyl polymers and natural oils and as an intermediate in the synthesis of glycerol, glycidyl ethers, and amines. It is also used as an alkylating agent, demulsifier, and dye-leveling agent and for sterilizing milk of magnesia. Glycidol is an alkylating agent which reacts readily with glutathione; it causes a decrease in glutathione content...

متن کامل

The effects of fungicide benomyl (benlate) on growth and mitosis in onion (Allium cepa L.) root apical meristem.

In this study, the effects of benomyl, a systemic fungicide were investigated in the mitotic cell division in onion (Allium cepa) root tip cells during germination. For this aim, different concentrations (1, 2, 5, 10 and 20 mM) of benomyl solutions were used. All the concentrations used caused several abnormalities in mitotic cell divisions and the mitotic frequency in the onion root tip cells ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Gazi university journal of science

سال: 2023

ISSN: ['2147-1762']

DOI: https://doi.org/10.35378/gujs.1218829